VHIR Annual Report 201

Vall d'Hebron. Institut de Recerca

Chronic Fatigue

José Alegre Martín


The research group in Chronic Fatigue at the Vall d’Hebron Research Institute in Barcelona, is currently working on creating a population-based registry of patients suffering from Chronic Fatigue Syndrome (CFS). Study the premorbid personality profile in CFS. Establishment of a DNA bank and study of genetic markers in patients and family members affected by this condition. We also studied the T cell response against pathogens in CFS

Research lines

  • Prevalence XRMV retrovirus infection in patients with chronic fatigue syndrome (CFS) and healthy blood donors, in Catalonia.Spain.
  • Genetic susceptibility factors in Chronic Fatigue Syndrome
  • Psycopathology of Chronic Fatigue Syndrome
  • Role of the nurses in the diagnostic and treatment of chronic fatigue syndrome
  • Population-based registry of chronic fatigue syndrome patients diagnoses in Spain.

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Total: 3

Impact Factor: 2.889

avg. impact factor: 0.963

Selected articles

Santamarina-Perez P, Freniche V, Eiroa-Orosa FJ, Llobet G, Saez N, Alegre J, Jacas C.
The role of depression in cognitive inpairment in patients with chronic fatigue  syndrome
Med Clin (Barc). 2011 Mar 12;136(6):239-243.
IF: 1.413

Ruiz E, Alegre J, Garcia Quintana AM, Aliste L, Blazquez A, Fernandez de Sevilla.
Chronic fatigue syndrome: study of a consecutive series of 824 cases assessed in two specialized units
Rev Clin Esp. 2011 Sep;211(8):385-90.
IF: 0.762

Santamarina-Perez P, Eiroa-Orosa FJ, Freniche V, Moreno-Mayos A, Alegre J, Saez N, Jacas C.
Length of illness does not predict cognitive dysfunction in chronic fatigue syndrome
Appl Neuropsychol. 2011 Jul;18(3):216-22.
IF: 0.714

Blazquez A. 1, Guillamò E. 1, Alegre J. 1, Javierre C.
Impact of psychological aspects on physiological response to stress in patients diagnosed with chronic fatigue syndrome
Minerva Psichiatrica 2011 March;52(1):11-19

Blazquez A, Guillamo E, Alegre J, Ventura JL, Barbany JR, Javierre C.
Cardiovascular responses to exercise in female chronic fatigue syndrome patients affect the psychological health ot their partners
J Exercise Physiology online 2011;14(2):1-16.

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